However that doesn't help with programs that are closed when I log back in, or things that open new windows, like Outlook opening a new email, it loads in the wrong spot, and I have to move it back to where I want it, which will be remembered until the next time the monitor goes into standby. I've also tried working around it with PersistentWindows from GitHub, I have tried working around it with DisplayFusion's Windows Location profiles, but some programs do not move into place still. It just seems that the DisplayPort connection being put to sleep is what's causing it to act like only one monitor of two is present, forcing everything into the 2nd monitor, but when when I wake the DisplayPort monitor, it just pushes most things to the far left of the screen and I have to re-arrange everything. I've already tried deleting all display configurations there too and rebooting so they get setup fresh, but no luck with that either. I've seen the posts on other forums about the NVIDIA Control panel overriding the EDID but that's only avaialble on Quatro cards, and other posts about the 'Simulated' monitor in the registry, but I checked and mine does not have a simulated entry. When I come back to it and log in again all my windows are in differnt places (top left) and I have to arrange them manually every time, which is a bit cumbersome to say the least, as I use the monitor for work during the day with lots of open windows in very specific locations. My PC itself is set to never sleep, but its set to sleep the monitor after 15 minutes of inactivity. I have a new ultrawide connected with DisplayPort, and a 2nd monitor connected via HDMI, and now I'm noticing everytime the monitor itself goes into Standby mode that my icons and window locations are all messed up.

Windows 10 resize after sleep